Virulence Gene Typing of Methicillin-susceptible Staphylococcus aureus (MSSA) Isolates in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)
Authors
Hassriana Fazilla Sapri
Nurul Azirah Mohamad Sani
Ainihayati Noordin
Hui-min Neoh
Salasawati Hussin
Abstract
We determined the presence of four virulence genes: (cna, seh, PVL, TSST-1) using multiplex PCR in 880 isolates of methicillin-susceptible Staphylococcus aureus (MSSA) collected from the Universiti Kebangsaan Malaysia Medical Centre (UKMMC) in 2009. We found that 51.59% (454/880) of the strains had cna; 21.82% (192/880) possessed seh; 10.23% (90/880) had PVL and 6.82% (60/880) haboured TSST-1. Although methicillin-susceptible, MSSA carries important virulence genes which could affect patient’s clinical course.
