Practice of Dietary Supplements and its Influence towards Treatment Adherence among Chronic Disease Patients
Keywords:
Supplement, Chronic disease, Knowledge, Attitude, AdherenceAbstract
Introduction: The use of dietary supplements had risen over the years among chronic disease patients with most of it were of patients' own initiative. As chronic disease patients were often prescribed with polypharmacy, concomitant use with supplements had led to concerns of treatment non-adherence. This study aimed to describe the supplements use, assess the knowledge and attitude towards supplements and its interaction with prescribed medication, and determine whether knowledge and attitude towards supplements could influence treatment adherence in chronic disease patients.
Methods: A cross-sectional study was conducted among chronic disease patients in a tertiary hospital in Malaysia from September to November 2016 upon their written informed consent.
Â
Results: A total number of 250 respondents were interviewed and 72.4% was found to use supplements of own initiatives. Most of the respondents were using supplements to maintain health (78.8%), prevent health problems (72.4%) and improve overall health (63.2%). It was found that respondents' knowledge on supplement-drug interactions were not at the satisfactory level. The treatment adherence was found not to be associated with knowledge and attitude towards supplements nor numbers of supplements use.
Â
Conclusion: Chronic disease patients mainly knew on the purpose of supplements for health and wellness, but had less knowledge on supplement-drug interactions, warranting patients' education on that particular field.
References
Ashar BH, Rowland-Seymour A. Advising Patients Who Use Dietary Supplements. Am J Med. 2018:121(2): 91-97.
Kelly JP, Kaufman DW, Kelley K, Rosenberg L, Anderson TE, Mitchell AA. Recent Trends in Use of Herbal and Other Natural Products. Arch Intern Med. 2005; 165(3): 281-286.
Ye Z, Song H. Antioxidant Vitamins Intake and the Risk of Coronary Heart Disease: Meta-Analysis of Cohort Studies. Eur J Prev Cardiol. 2008;15(1): 26-34.
Timbo BB, Ross MP, Mccarthy PV, Lin,CTJ. Dietary Supplements in a National Survey: Prevalence of Use and Reports of Adverse Events. J Am Diet Assoc.2006; 106(12): 1966-1974.
Stupay S, Sivertsen L. Herbal and Nutritional Supplement Use in the Elderly. Nurse Pract. 2002;25(9): 56-67.
Huang HY, Caballero B, Chang S, Alberg AJ, Semba RD, Schneyer C, Wilson RF, Cheng TY, Prokopowicz G, Barnes GJ. Multivitamin/Mineral Supplements and Prevention of Chronic Disease: Executive Summary. Am J Clin Nutr. 2007; 85(1): 265S-268S.
Field TS, Gurwitz JH, Harrold LR, Rothschild J, Debellis KR, Seger AC, Auger JC, Garber LA, Cadoret C, Fish LS. Risk Factors for Adverse Drug Events among Older Adults in the Ambulatory Setting. J Am Geriatr Soc. 2004; 52(8): 1349-1354.
Wold RS, Lopez ST, Yau CL, Butler LM, Pareo-Tubbeh SL, Waters DL, Garry PJ, Baumgartner RN. Increasing Trends in Elderly Persons' Use of Nonvitamin, Nonmineral Dietary Supplements and Concurrent Use of Medications. J Am Diet Assoc. 2005; 105(1): 54-63.
Ambrose ET, Samuels S. Perception and Use of Herbals among Students and Their Practitioners in a University Setting. J Am Acad Nurse Pract. 2004; 16(4): 166-173.
Yilmaz MB, Yontar OC, Turgut OO, Yilmaz A, Yalta K, Gul M, Tandogan I. Herbals in Cardiovascular Practice: Are Physicians Neglecting Anything? International Journal of Cardiology. 2007; 122(1): 48-51.
Samojlik I, Mijatović V, Gavarić N, Krstin S, Božin B. Consumers’ Attitude Towards the Use and Safety of Herbal Medicines and Herbal Dietary Supplements in Serbia. Int J Clin Pharm. 2013; 35(5): 835-840.
Bebeçi E, Papajani V, Risto J. Knowledge and Awareness of Nutritional Supplements and Drug Interactions and the Role of Pharmacist in the Prevention. Age. 2015; 18(24): 35.
Steinman MA, Landefeld C, Rosenthal GE, Berthenthal D, Sen S, Kaboli PJ. Polypharmacy and Prescribing Quality in Older People. J Am Geriatr Soc. 2006; 54(10): 1516-1523.
Maraldi C, Lattanzio F, Onder G, Gallerani M, Bustacchini S, De Tommaso G, Volpato S. Variability in the Prescription of Cardiovascular Medications in Older Patients. Drugs Aging. 2009; 26(1): 41-51.
Bailey RL, Gahche JJ, Miller PE, Thomas PR, Dwyer JT. Why Us Adults Use Dietary Supplements. JAMA Intern Med. 2013;173(5): 355-361.
Owens C, Toone T, Steed-Ivie M. A Survey of Dietary Supplement Knowledge, Attitudes, and Use in a Rural Population. J Nutr Food Sci 2014; 4:304.
Kripalani S, Risser J, Gatti ME, Jacobson TA. Development and Evaluation of the Adherence to Refills and Medications Scale (Arms) among Lowâ€Literacy Patients with Chronic Disease. Value Health. 2009; 12(1): 118-123.
Gardiner P, Graham R, Legedza AT, Ahn AC. Factors Associated with Herbal Therapy Use by Adults in the United States. Altern Ther Health Med. 2007; 13(2): 22.
Marinac JS, Buchinger CL, Godfrey LA, Wooten JM, Sun C, Willsie SK. Herbal Products and Dietary Supplements: A Survey of Use, Attitudes, and Knowledge among Older Adults. J Am Osteopath Assoc. 2007; 107(1): 13-23.
Axon DR, Vanova J, Edel C, Slack M. Dietary Supplement Use, Knowledge, and Perceptions Among Student Pharmacists. Am J Pharm Educ. 2017;81(5):92
Morris CA, Avorn J. Internet Marketing of Herbal Products. JAMA. 2003; 290(11): 1505-1509.
Fotuhi M, Zandi PP, Hayden KM, Khachaturian AS, Szekely CA, Wengreen H, Munger RG, Norton MC, Tschanz JT, Lyketsos CG. Better Cognitive Performance in Elderly Taking Antioxidant Vitamins E and C Supplements in Combination with Nonsteroidal Anti-Inflammatory Drugs: The Cache County Study. Alzheimers Dement. 2008;4(3): 223-227.
Lappe JM, Travers-Gustafson D, Davies KM, Recker RR, Heaney RP. Vitamin D and Calcium Supplementation Reduces Cancer Risk: Results of a Randomized Trial. Am J Clin Nutr. 2007; 85(6): 1586-1591.
Klein JD, Wilson KM, Sesselberg TS, Gray NJ, Yussman S, West J. Adolescents’ Knowledge of and Beliefs About Herbs and Dietary Supplements: A Qualitative Study. J Adolesc Health. 2005; 37(5): 409.
Archer SL. Nonvitamin and Nonmineral Supplement Use among Elderly People. J Am Diet Assoc. 2005;105(1): 63-64.
