Prevalence And Correlates Of Parkinson’s Disease Among Elderly Patients Attending Neurology Clinic At Serdang Hospital In 2016


  • Halimatus Sakdiah Minhat Universiti Putra Malaysia


Prevalence – Correlates - Parkinson’s Disease - Elderly


Introduction   Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease (AD) and the most frequent sub-cortical degenerative disease, characterized by universal progressive disorder of the nervous system that affects movement.


Methodology  This cross sectional study aimed to determine the prevalence and correlates of PD among elderly attending the neurology clinic in Serdang Hospital. A total of 150 records of patients attended the clinic from January to December were randomly selected. Data was collected using a proforma form seeking information related to age, gender, race, locality, and presence of comorbidity particularly diabetes mellitus.


Result The data was analysed using the Statistical Package for Social Science (IBM SPSS) version 22.0. The prevalence of PD among the elderly involved in the study was 34%. Majority of the respondents were aged 60 to 70 years old (54.7%), male (53.3%), Chinese (56.7%), from urban locality (93.0%) and were not diabetic (69.3%). The inferential statistics showed no significant association between all the factors with PD. However, the associations between age and diabetes mellitus with PD were almost significant with p values of 0.07 and 0.08 respectively.


Conclusion     Overall, the prevalence of PD among elderly who attended the neurology clinic in year 2016 was less than half with none of the factors under study were significantly associated with PD. However with bigger sample size, possible significant association may be obtained between age and diabetes mellitus. 


Kubis N, Faucheux BA, Ransmayr G, Damier P, Duyckaerts C, Henin D, Forette B, Le Charpentier Y, Hauw JJ, Agid Y, Hirsch EC. Preservation of midbrain catecholaminergic neurons in very old human subjects. Brain.2000;123:366-373.

Tanner CM Parkinson's disease. In: Gorelick PB, Alter M, eds. Handbook of Neuroepidemiology. New York, NY: Marcel Dekker Inc; 1994:253-280.

Aevarsson O, Svanborg A, Skoog I. Seven-year survival rate after age 85 years: relation to Alzheimer's disease and vascular dementia. Arch Neurol.1998;55:1226-1232.

Nico JD, Charity GM, Sue EL, Teresa AC, Christopher GG. Parkinson Disease With Old-Age Onset: A Comparative Study With Subjects With Middle-Age Onset. Arch Neurol. 2003;60(4):529-533. doi:10.1001/archneur.60.4.529

Tison F, Dartigues JF, Dubes L, Zuber M, Alperovitch A, Henry P. Prevalence of Parkinson's disease in the elderly: a population study in Gironde, France. Acta Neurol Scand. 1994 Aug;90(2):111-5.

De Rijk MC, Breteler MM, Graveland GA, Ott A, Grobbee DE, Van der Meché FG, Hofman A. Prevalence of Parkinson's disease in the elderly: the Rotterdam Study. Neurology. 1995 Dec;45(12):2143-6.

Gordon PH, Mehal JM, Holman RC, Bartholomew ML, Cheek JE, Rowland AS. Incidence and prevalence of Parkinson's disease among Navajo people living in the Navajo nation. Mov Disord. 2015 Apr 15;30(5):714-20. doi: 10.1002/mds.26147.

Van de Vijver DA, Roos RA, Jansen PA, Porsius AJ, de Boer A. Estimation of incidence and prevalence of Parkinson's disease in the elderly using pharmacy records. Pharmacoepidemiol Drug Saf. 2001 Oct-Nov;10(6):549-54.

De Rijk MC, Tzourio C, Breteler MB, Dartigues JF, Amaducci L, Lopez-Pousa S, Manubens-Bertran JM, Alperovitch A, Rocca WA. Prevalence of Parkinsonism and Parkinson's disease in Europe: The EUROPARKINSON collaborative study. lof Neurology, Neurosurgery, and Psychiatry 1997;62:10-15.

Schapira AH. Mitochondria in the aetiology and pathogenesis of Parkinson's disease. Lancet Neurol 2008;7:97–109.

Sun Y, Chang YH, Chen HF, Su YH, Su HF, Li CY . Risk of Parkinson disease onset in patients with diabetes: a 9-year population-based cohort study with age and sex stratifications. Diabetes Care 2012;35:1047–9.

Santiago JA, Potashkin JA. Shared dysregulated pathways lead to Parkinson's disease and diabetes. Trends Mol Med 2013;19:176–86.

Lu L, Fu DL, Li HQ, Liu AJ, Li JH, Zheng GQ. Diabetes and risk of Parkinson's disease: an updated meta-analysis of case-control studies. PLoS ONE 2014;9:e85781.

Saguil A, Lax JW. Acute migraine treatment in emergency settings. Am Fam Physician 2014;89:742–4.

Yang YW, Hsieh TF, Li CI, Liu CS, Lin WY, Chiang JH, Li TC, Lin CC. Increased risk of Parkinson disease with diabetes mellitus in a population-based study. Medicine (Baltimore). 2017 Jan; 96(3): e5921. doi: 10.1097/MD.0000000000005921.




How to Cite

Minhat, H. S. (2018). Prevalence And Correlates Of Parkinson’s Disease Among Elderly Patients Attending Neurology Clinic At Serdang Hospital In 2016. International Journal of Public Health Research, 8(1), 894–898. Retrieved from