@article{Yu_Yan_Fong_Muhammad_Said Abu Hass_2022, title={Aetiologies of Liver Cirrhosis among Adult Patients attending a Hepatology Clinic at Selangor, Malaysia}, volume={12}, url={https://spaj.ukm.my/ijphr/index.php/ijphr/article/view/309}, abstractNote={<p><strong>Introduction:</strong> Liver cirrhosis is an important cause of morbidity and mortality.</p> <p><strong>Methods: </strong>Our study aimed to describe the clinical pattern of cirrhosis and its associated factors among adult patients attending Hepatology Clinic, Serdang Hospital, Malaysia from 1<sup>st</sup> January 2010 to 30<sup>th </sup>June 2017. Aetiology was further determined by history, biochemistry and/or histology. The severity of the cirrhosis, together with the presence of complications and incidence of hepatocellular carcinoma were documented.</p> <p><strong>Results: </strong>A total of 357 adult patients were diagnosed with cirrhosis including 199 male patients (55.7%) and 158 female patients (44.3%), with a mean age of 54-year-old (range: 28–84 –year-old). The causes of cirrhosis were chronic hepatitis B (N=145, 40.6%), chronic hepatitis C (N= 67, 18.8%), cryptogenic liver disorder (N= 63, 17.6%), alcohol (N=42, 11.8%), non-alcoholic fatty liver disease (N=25, 7.0%), and others (N=15, 4.2%). Chronic hepatitis B was the predominant aetiology among Chinese whereas alcohol was the main aetiology among Indians, and Hepatitis C cirrhosis was highest among Malays. Majority of the patients had compensated cirrhosis with Child-Pugh A (N=221, 61.9%) at the time of diagnosis. 80.4% (N=287) of the cirrhotic patients had performed at least one endoscopy surveillance, with 28.6% (82/287) of them had endoscopic evidence of portal hypertension. 32.2% of patients had at least one hospitalization due to complication of cirrhosis. 41 patients (11.5%) had concurrent hepatocellular carcinoma during the follow up.</p> <p><strong>Conclusions: </strong>Despite universal hepatitis B vaccination, Hepatitis B viral infection remains the most common cause of cirrhosis among patients attending Hepatology Clinic, Serdang Hospital. </p> <p><strong>Keywords: Aetiology - Liver cirrhosis - Malaysia</strong></p>}, number={1}, journal={International Journal of Public Health Research}, author={Yu, Chieng Jin and Yan, Pan and Fong, Liew Chiat and Muhammad, Mazawawi and Said Abu Hass, Syed Anas Tamamulqomar}, year={2022}, month={Feb.} }